Ocular Surface Disease Severity in Polycystic Ovary Syndrome: is This Really Significant in Daily Life?

OBJECTIVE: The purpose of this study was to ascertain the extent which ocular surface women with polycystic ovary syndrome is impacted. STUDY DESIGN: Included in case-control were 23 eyes patients (Group I) and 10 healthy subjects II). Polycystic diagnosed when two following conditions met: oligo- or anovulation, clinical and/or biochemical signs hyperandrogenism, ultrasonographic documentation ovaries. Ocular disease grading performed using Surface Disease Index questionnaire, slit lamp examination, meibomian gland secretion scoring, tear film breakup time, staining scores surfaces, Schirmer's test, osmolarity assessment. RESULTS: observed no significant difference age (p=0.896). Group I found have a significantly higher median luteinizing hormone level (p=0.027). group than those II (p=0.031). prevalence anterior blepharitis greater (p=0.05). Tear time (p=0.026). severity be (p=0.03). In I, positively correlated free testosterone, while estradiol levels but negatively dehydroepiandrosterone sulfate (p<0.05). CONCLUSIONS: Daily activities appear slightly impaired due problems. However, environmental factors (humidity, temperature, etc.) contribute aggravation symptoms. Patients may referred an ophthalmologist preserve health.